Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines

Robert Steel, Lara Buchak, Nir Eyal

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection (or 'challenge') trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.

Original languageEnglish (US)
Pages (from-to)808-812
Number of pages5
JournalJournal of Medical Ethics
Volume46
Issue number12
DOIs
StatePublished - Dec 1 2020

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Arts and Humanities (miscellaneous)
  • Health Policy
  • Issues, ethics and legal aspects

Keywords

  • clinical trials
  • ethics
  • philosophical ethics
  • research ethics

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