Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria

Richard P. Novick; Tom W. Muir

doi:10.1016/S1369-5274(99)80007-1

Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria

Richard P. Novick, Tom W. Muir

Research output: Contribution to journal › Article › peer-review

134 Scopus citations

Abstract

In staphylococci, autoinducing peptides activate agr, a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure- function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.

Original language	English (US)
Pages (from-to)	40-45
Number of pages	6
Journal	Current opinion in microbiology
Volume	2
Issue number	1
DOIs	https://doi.org/10.1016/S1369-5274(99)80007-1
State	Published - Feb 1 1999
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.1016/S1369-5274(99)80007-1

Cite this

@article{62ae2c07389348d5a533c92083ba1b23,

title = "Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria",

abstract = "In staphylococci, autoinducing peptides activate agr, a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure- function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.",

author = "Novick, {Richard P.} and Muir, {Tom W.}",

year = "1999",

month = feb,

day = "1",

doi = "10.1016/S1369-5274(99)80007-1",

language = "English (US)",

volume = "2",

pages = "40--45",

journal = "Current opinion in microbiology",

issn = "1369-5274",

publisher = "Elsevier Limited",

number = "1",

}

TY - JOUR

T1 - Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria

AU - Novick, Richard P.

AU - Muir, Tom W.

PY - 1999/2/1

Y1 - 1999/2/1

N2 - In staphylococci, autoinducing peptides activate agr, a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure- function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.

AB - In staphylococci, autoinducing peptides activate agr, a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure- function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.

UR - http://www.scopus.com/inward/record.url?scp=0033057730&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033057730&partnerID=8YFLogxK

U2 - 10.1016/S1369-5274(99)80007-1

DO - 10.1016/S1369-5274(99)80007-1

M3 - Article

C2 - 10047551

AN - SCOPUS:0033057730

SN - 1369-5274

VL - 2

SP - 40

EP - 45

JO - Current opinion in microbiology

JF - Current opinion in microbiology

IS - 1

ER -

Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this