Virulence gene regulation by peptides in staphylococci and other gram- positive bacteria

Richard P. Novick, Thomas William Muir

Research output: Contribution to journalArticlepeer-review

121 Scopus citations

Abstract

In staphylococci, autoinducing peptides activate agr, a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure- function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.

Original languageEnglish (US)
Pages (from-to)40-45
Number of pages6
JournalCurrent Opinion in Microbiology
Volume2
Issue number1
DOIs
StatePublished - Feb 1 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases

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