@article{3bb0df5a1c4d49d99e8711a29dca705e,
title = "Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation",
abstract = "Aim: The mathematical method used to calculate chest compression (CC) rate during cardiopulmonary resuscitation varies in the literature and across device manufacturers. The objective of this study was to determine the variability in calculated CC rates by applying four published methods to the same dataset. Methods: This study was a secondary investigation of the first 200 pediatric cardiac arrest events with invasive arterial line waveform data in the ICU-RESUScitation Project (NCT02837497). Instantaneous CC rates were calculated during periods of uninterrupted CCs. The defined minimum interruption length affects rate calculation (e.g., if an interruption is defined as a break in CCs ≥ 2 s, the lowest possible calculated rate is 30 CCs/min). Average rates were calculated by four methods: 1) rate with an interruption defined as ≥ 1 s; 2) interruption ≥ 2 s; 3) interruption ≥ 3 s; 4) method #3 excluding top and bottom quartiles of calculated rates. American Heart Association Guideline-compliant rate was defined as 100–120 CCs/min. A clinically important change was defined as ±5 CCs/min. The percentage of events and epochs (30 s periods) that changed Guideline-compliant status was calculated. Results: Across calculation methods, mean CC rates (118.7–119.5/min) were similar. Comparing all methods, 14 events (7%) and 114 epochs (6%) changed Guideline-compliant status. Conclusion: Using four published methods for calculating CC rate, average rates were similar, but 7% of events changed Guideline-compliant status. These data suggest that a uniform calculation method (interruption ≥ 1 s) should be adopted to decrease variability in resuscitation science.",
keywords = "American Heart Association Guideline, Cardiopulmonary resuscitation, Chest compression rate",
author = "{the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators the National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators} and Landis, {William P.} and Morgan, {Ryan W.} and Reeder, {Ron W.} and Kathryn Graham and Ashley Siems and Diddle, {J. Wesley} and Pollack, {Murray M.} and Tensing Maa and Fernandez, {Richard P.} and Yates, {Andrew R.} and Bradley Tilford and Tageldin Ahmed and Meert, {Kathleen L.} and Carleen Schneiter and Robert Bishop and Mourani, {Peter M.} and Naim, {Maryam Y.} and Stuart Friess and Candice Burns and Arushi Manga and Deborah Franzon and Sarah Tabbutt and McQuillen, {Patrick S.} and Horvat, {Christopher M.} and Matthew Bochkoris and Carcillo, {Joseph A.} and Leanna Huard and Myke Federman and Anil Sapru and Shirley Viteri and Hehir, {David A.} and Notterman, {Daniel A.} and Richard Holubkov and Dean, {J. Michael} and Nadkarni, {Vinay M.} and Berg, {Robert A.} and Wolfe, {Heather A.} and Sutton, {Robert M.} and Zuppa, {Athena F.} and Martha Sisko and Wessel, {David L.} and Elyse Tomanio and Hall, {Mark W.} and Lisa Steele and Sabrina Heidemann and Ann Pawluszka and Todd Carpenter and Ruth Grosskreuz and Tina Day and Anne McKenzie",
note = "Funding Information: Financial support was provided through the Department of Anesthesiology and Critical Care Medicine at The Children{\textquoteright}s Hospital of Philadelphia, the ICU-RESUScitation Project , and CPCCRN . Funding Information: Financial support was provided through the Department of Anesthesiology and Critical Care Medicine at The Children's Hospital of Philadelphia, the ICU-RESUScitation Project, and CPCCRN.Supported, in part, by the following cooperative agreements from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services: R01HL131544, UG1HD063108, and U01HD049934. Funding Information: Supported, in part, by the following cooperative agreements from the Eunice Kennedy Shriver National Institute of Child Health and Human Development , National Institutes of Health , Department of Health and Human Services : R01HL131544 , UG1HD063108 , and U01HD049934 . Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",
year = "2020",
month = apr,
doi = "10.1016/j.resuscitation.2020.01.040",
language = "English (US)",
volume = "149",
pages = "127--133",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",
}