Using synthetic RNAs as scaffolds and regulators

Cameron Myhrvold; Pamela A. Silver

doi:10.1038/nsmb.2944

Using synthetic RNAs as scaffolds and regulators

Cameron Myhrvold
, Pamela A. Silver

Research output: Contribution to journal › Comment/debate › peer-review

26 Scopus citations

Abstract

The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.

Original language	English (US)
Pages (from-to)	8-10
Number of pages	3
Journal	Nature Structural and Molecular Biology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1038/nsmb.2944
State	Published - Jan 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Structural Biology

Access to Document

10.1038/nsmb.2944

Cite this

@article{a62085c81bf74936a17ce6c93539a7bd,

title = "Using synthetic RNAs as scaffolds and regulators",

abstract = "The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.",

author = "Cameron Myhrvold and Silver, \{Pamela A.\}",

year = "2015",

month = jan,

day = "1",

doi = "10.1038/nsmb.2944",

language = "English (US)",

volume = "22",

pages = "8--10",

journal = "Nature Structural and Molecular Biology",

issn = "1545-9993",

publisher = "Nature Research",

number = "1",

}

TY - JOUR

T1 - Using synthetic RNAs as scaffolds and regulators

AU - Myhrvold, Cameron

AU - Silver, Pamela A.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.

AB - The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.

UR - https://www.scopus.com/pages/publications/84925283926

UR - https://www.scopus.com/pages/publications/84925283926#tab=citedBy

U2 - 10.1038/nsmb.2944

DO - 10.1038/nsmb.2944

M3 - Comment/debate

C2 - 25565027

AN - SCOPUS:84925283926

SN - 1545-9993

VL - 22

SP - 8

EP - 10

JO - Nature Structural and Molecular Biology

JF - Nature Structural and Molecular Biology

IS - 1

ER -

Using synthetic RNAs as scaffolds and regulators

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this