Using synthetic RNAs as scaffolds and regulators

Cameron Myhrvold; Pamela A. Silver

doi:10.1038/nsmb.2944

Using synthetic RNAs as scaffolds and regulators

Cameron Myhrvold, Pamela A. Silver

Research output: Contribution to journal › Comment/debate › peer-review

25 Scopus citations

Abstract

The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.

Original language	English (US)
Pages (from-to)	8-10
Number of pages	3
Journal	Nature Structural and Molecular Biology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1038/nsmb.2944
State	Published - Jan 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Structural Biology

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10.1038/nsmb.2944

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Using synthetic RNAs as scaffolds and regulators

Abstract

All Science Journal Classification (ASJC) codes

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