Using synthetic RNAs as scaffolds and regulators

Cameron Myhrvold, Pamela A. Silver

Research output: Contribution to journalComment/debatepeer-review

23 Scopus citations


The natural versatility of RNA makes it an ideal substrate for bioengineering. Its structural properties and predictable base-pairing permit its use as molecular scaffold, and its ability to interact with nucleic acids, proteins and small molecules confers a regulatory potential that can be harvested to design RNA regulators in diverse contexts.

Original languageEnglish (US)
Pages (from-to)8-10
Number of pages3
JournalNature Structural and Molecular Biology
Issue number1
StatePublished - Jan 1 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Structural Biology


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