Using bioMEMS to control cellular microenvironments

Christopher Chen, Joe Tien, John Tan, Celeste Nelson

Research output: Contribution to journalConference article

Abstract

Cells were examined on how to recognize and respond to adhesive interactions with the insoluble extracellular matrix (ECM) by using conventional and non-conventional microfabrication approaches to engineer well-defined cellular microenvironments. Control and monitoring of compositional chemistry, mechanical properties, architecture and geometry of the adhesive interactions were addressed as well as the resulting progress in identifying and elucidating the mechanisms by which cells sense the physical, chemical, and structural information carried within the ECM.

Original languageEnglish (US)
Pages (from-to)S-80
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Externally publishedYes
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

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