Use of sub-10 nm diameter upconversion nanophosphors as bio-labels

Shuang Fang Lim, Robert Riehn, Chih Kuan Tung, David Tank, William S. Ryu, Nan Yao, Robert H. Austin

Research output: Chapter in Book/Report/Conference proceedingConference contribution


We have synthesized rare-earth doped sub-10 nm diameter upconverting yttrium oxide based nanophosphors by flame spray pyrolysis. We have investigated the emitted visible fluorescence of the sub-10nm nanophosphors under both infrared excitation and electron excitation, and observed comparable narrow band emission spectra. The viability of the nanoparticles for biological imaging was confirmed by imaging the digestive system of the nematode worm C. elegans in the upconversion mode. We have surface functionalized the nanophosphors making them suitable for bio labeling.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium Proceedings
PublisherMaterials Research Society
Number of pages6
ISBN (Print)9781604234060
StatePublished - 2006
Event2006 MRS Fall Meeting - Boston, MA, United States
Duration: Nov 27 2006Dec 1 2006

Publication series

NameMaterials Research Society Symposium Proceedings
ISSN (Print)0272-9172


Other2006 MRS Fall Meeting
Country/TerritoryUnited States
CityBoston, MA

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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