Two-photon imaging of intracellular hydrogen peroxide with a chemoselective fluorescence probe

  • Hengchang Guo
  • , Hossein Aleyasin
  • , Scott Howard
  • , Bryan C. Dickinson
  • , Renee Haskew-Layton
  • , Demirhan Kobat
  • , Vivian S. Lin
  • , David Rivera
  • , Christopher J. Chang
  • , Rajiv R. Ratan
  • , Chris Xu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present two-photon imaging of hydrogen peroxide (H2O2) production in mouse hippocampal neuronal cell line (HT22) using Peroxyfluor-6 acetoxymethyl ester (PF6-AM), a highly sensitive, small-molecule probe for selective imaging of H2O2 within the living cells.

Original languageEnglish (US)
Title of host publicationOptical Molecular Probes, Imaging and Drug Delivery, OMP 2011
PublisherOptical Society of America (OSA)
ISBN (Print)9781557529091
DOIs
StatePublished - 2011
Externally publishedYes
EventOptical Molecular Probes, Imaging and Drug Delivery, OMP 2011 - Monterey, CA, United States
Duration: Apr 4 2011Apr 6 2011

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceOptical Molecular Probes, Imaging and Drug Delivery, OMP 2011
Country/TerritoryUnited States
CityMonterey, CA
Period4/4/114/6/11

All Science Journal Classification (ASJC) codes

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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