Two domains and one RNA: A molecular threesome

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

Structures of the Drosophila Sex-lethal protein with and without bound RNA reveal an unexpected mode of binding in which tripartite interactions between the two RNA-binding domains and the bound RNA generate specific, high-affinity binding.

Original languageEnglish (US)
Pages (from-to)499-502
Number of pages4
JournalNature Structural Biology
Volume6
Issue number6
DOIs
StatePublished - Jun 9 1999

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biochemistry
  • Genetics

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