WOCl4 catalyzes dehydrative decarboxylation of 2,3-dihydroxycarboxylic acids to enols, likely via β-lactone intermediates. Classical reagents for conversion of 3-hydroxycarboxylic acids to β-lactones fail with these substrates.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Nov 3 1992|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry