Tunable multi-wavelength resonance-Raman detection of bacteria and chemicals in complex environments

Jacob Grun, Jeffrey Bowles, David Gillis, Pratima Kunapareddy, Robert Lunsford, Charles K. Manka, Sergei Nikitin, Zheng Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

We are developing tunable-multi-wavelength resonance-Raman spectroscopy and algorithms to enable rapid detection and identification of bacteria and chemicals in complex environments. The system, dubbed SWOrRD, is capable of illuminating a sample containing many chemicals or biological agents with a sequence of laser wavelengths between 210nm and 2000nm; a range which encompasses the resonant frequencies of cells, microorganisms, cellular metabolites, and many chemicals; and measures the resonance-Raman spectra of light scattered from the sample at each laser wavelength. These multiple spectra, which contain much more information about the bond structure that is contained in a single spectrum, are analyzed by a linear-mixture algorithm, based on NRL's ORASIS, to determine the chemical and bacteriological constituents of the sample. The current status of the research will be described.

Original languageEnglish (US)
Title of host publicationActive and Passive Signatures
DOIs
StatePublished - 2010
Externally publishedYes
EventActive and Passive Signatures - Orlando, FL, United States
Duration: Apr 8 2010Apr 9 2010

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume7687
ISSN (Print)0277-786X

Conference

ConferenceActive and Passive Signatures
Country/TerritoryUnited States
CityOrlando, FL
Period4/8/104/9/10

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Keywords

  • detection
  • Multi wavelength
  • Raman
  • resonance
  • resonance-Raman
  • signatures

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