Transcriptional repression in development

Susan Gray; Michael Levine

doi:10.1016/S0955-0674(96)80010-X

Transcriptional repression in development

Susan Gray, Michael Levine

Research output: Contribution to journal › Article › peer-review

150 Scopus citations

Abstract

It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.

Original language	English (US)
Pages (from-to)	358-364
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	8
Issue number	3
DOIs	https://doi.org/10.1016/S0955-0674(96)80010-X
State	Published - Jun 1996
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cell Biology

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10.1016/S0955-0674(96)80010-X

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title = "Transcriptional repression in development",

abstract = "It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.",

author = "Susan Gray and Michael Levine",

year = "1996",

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AB - It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.

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U2 - 10.1016/S0955-0674(96)80010-X

DO - 10.1016/S0955-0674(96)80010-X

M3 - Article

C2 - 8743887

AN - SCOPUS:0029895168

SN - 0955-0674

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SP - 358

EP - 364

JO - Current Opinion in Cell Biology

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IS - 3

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Transcriptional repression in development

Abstract

All Science Journal Classification (ASJC) codes

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