Transcriptional repression in development

Susan Gray, Michael Levine

Research output: Contribution to journalArticle

141 Scopus citations

Abstract

It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.

Original languageEnglish (US)
Pages (from-to)358-364
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume8
Issue number3
DOIs
StatePublished - Jun 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cell Biology

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