A practical stereospecific synthesis of thienamycin 1 has been achieved. Key steps include a lead tetracetate oxidative decarboxylation and subsequent insertion of a four carbon diazo containing unit into a 3-acetoxy-2-azetidinene.
|Original language||English (US)|
|Number of pages||4|
|State||Published - 1982|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry