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Three-dimensional structures of Plasmodium falciparum spermidine synthase with bound inhibitors suggest new strategies for drug design
Janina Sprenger
, Bo Svensson
, Jenny Hålander
,
Jannette Carey
, Lo Persson
, Salam Al-Karadaghi
Chemistry
Molecular Biology
Princeton Materials Institute
Research output
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Contribution to journal
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Article
›
peer-review
13
Scopus citations
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Dive into the research topics of 'Three-dimensional structures of Plasmodium falciparum spermidine synthase with bound inhibitors suggest new strategies for drug design'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Plasmodium falciparum
100%
Spermidine Synthase
100%
Binding Site
66%
Ligand Binding
33%
Active Site
33%
Anabolism
33%
Crystal Structure
33%
S-Adenosyl Methionine
33%
Computer Model
33%
X-Ray Crystallography
33%
Plasmodium
33%
Keyphrases
Methylthioadenosine
100%
Aniline Compounds
25%
Polyamine Biosynthesis
25%
In Silico Screening
25%
N-methylaniline
25%
Pharmacology, Toxicology and Pharmaceutical Science
Polyamine
33%
Aniline Derivative
33%
4 Methylaniline
33%