Three-dimensional chiral imaging by sum-frequency generation

Na Ji, Kai Zhang, Haw Yang, Yuen Ron Shen

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


A sum-frequency generation (SFG) microscope that is sensitive toward molecular chirality was demonstrated for the first time. Optically active images of chiral 1,1′-bi-2-naphthol solutions were obtained with submicron spatial resolution. Three-dimensional sectioning capability of our microscope was also demonstrated. This optically active SFG microscopy can potentially become a powerful imaging technique for biological samples.

Original languageEnglish (US)
Pages (from-to)3482-3483
Number of pages2
JournalJournal of the American Chemical Society
Issue number11
StatePublished - Mar 22 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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