Thermogenesis detection of single living cells via quantum dots

Jui Ming Yang, Haw Yang, Liwei Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations

Abstract

Cellular endocytotic quantum dots (QDs) have been successfully used as thermometers to sense temperature variations inside single living cells. Temperature changes have been detected remotely through optical readout. We showed the increased extracellular calcium concentration can trigger the thermogenesis of NIH/3T3 cells and therefore elevated the cellular temperature about 1.5 °C. This technique has the potential as nanoscale thermometers for intracellular temperature measurements using non-contact, far field optical instruments with combination of both diffraction-limited spatial resolution at about 700 nm and sampling-rate-limited temporal resolution at about 30-100 ms.

Original languageEnglish (US)
Title of host publicationMEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest
Pages963-966
Number of pages4
DOIs
StatePublished - Jun 1 2010
Event23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong, China
Duration: Jan 24 2010Jan 28 2010

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

Other23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
CountryChina
CityHong Kong
Period1/24/101/28/10

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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  • Cite this

    Yang, J. M., Yang, H., & Lin, L. (2010). Thermogenesis detection of single living cells via quantum dots. In MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest (pp. 963-966). [5442368] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2010.5442368