Theory and evaluation of single-molecule signals

Eli Barkai, Frank L.H. Brown, Michel Orrit, Haw Yang

Research output: Book/ReportBook

45 Scopus citations


This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitatively differs from those obtained in conventional experiments on large ensembles of molecules. Fluctuations, randomness and irreproducibility are central to single-molecule measurements, and the specific methods required to extract reliable and statistically relevant information from them are presented here. With contributions mainly from participants of the “Theory, Modeling and Evaluation of Single-Molecule Measurements” workshop held in Leiden, the Netherlands, on April 16-20, 2007, this book is an authoritative compendium on the subject.

Original languageEnglish (US)
PublisherWorld Scientific Publishing Co.
Number of pages399
ISBN (Electronic)9789812793492
ISBN (Print)9812793488, 9789812793485
StatePublished - Jan 1 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry


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