The Uranyl Cation as a Visible-Light Photocatalyst for C(sp3)−H Fluorination

Julian G. West; T. Aaron Bedell; Erik J. Sorensen

doi:10.1002/anie.201603149

The Uranyl Cation as a Visible-Light Photocatalyst for C(sp³)−H Fluorination

Julian G. West, T. Aaron Bedell, Erik J. Sorensen

Chemistry

Research output: Contribution to journal › Article › peer-review

153 Scopus citations

Abstract

The fluorination of unactivated C(sp³)−H bonds remains a desirable and challenging transformation for pharmaceutical, agricultural, and materials scientists. Previous methods for this transformation have used bench-stable fluorine atom sources; however, many still rely on the use of UV-active photocatalysts for the requisite high-energy hydrogen atom abstraction event. Uranyl nitrate hexahydrate is described as a convenient, hydrogen atom abstraction catalyst that can mediate fluorinations of certain alkanes upon activation with visible light.

Original language	English (US)
Pages (from-to)	8923-8927
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	55
Issue number	31
DOIs	https://doi.org/10.1002/anie.201603149
State	Published - Jul 25 2016

All Science Journal Classification (ASJC) codes

General Chemistry
Catalysis

Keywords

C−H activation
fluorination
hydrogen atom transfer
photocatalysis
uranium

Access to Document

10.1002/anie.201603149

Cite this

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abstract = "The fluorination of unactivated C(sp3)−H bonds remains a desirable and challenging transformation for pharmaceutical, agricultural, and materials scientists. Previous methods for this transformation have used bench-stable fluorine atom sources; however, many still rely on the use of UV-active photocatalysts for the requisite high-energy hydrogen atom abstraction event. Uranyl nitrate hexahydrate is described as a convenient, hydrogen atom abstraction catalyst that can mediate fluorinations of certain alkanes upon activation with visible light.",

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