The termination of translation

Sabine Petry; Albert Weixlbaumer; V. Ramakrishnan

doi:10.1016/j.sbi.2007.11.005

The termination of translation

Sabine Petry
, Albert Weixlbaumer
, V. Ramakrishnan

Research output: Contribution to journal › Review article › peer-review

56 Scopus citations

Abstract

Recent results from cryoelectron microscopy, crystallography, and biochemical experiments have shed considerable light on the process by which protein synthesis is terminated when a stop codon is reached. However, a detailed understanding of the underlying mechanisms will require higher-resolution structures of the various states involved.

Original language	English (US)
Pages (from-to)	70-77
Number of pages	8
Journal	Current Opinion in Structural Biology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/j.sbi.2007.11.005
State	Published - Feb 2008
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Structural Biology

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10.1016/j.sbi.2007.11.005

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title = "The termination of translation",

abstract = "Recent results from cryoelectron microscopy, crystallography, and biochemical experiments have shed considerable light on the process by which protein synthesis is terminated when a stop codon is reached. However, a detailed understanding of the underlying mechanisms will require higher-resolution structures of the various states involved.",

author = "Sabine Petry and Albert Weixlbaumer and V. Ramakrishnan",

note = "Funding Information: Work in the authors{\textquoteright} laboratory was supported by the Medical Research Council (UK) and grants from the US National Institutes of Health and the Agouron Institute. SP was partly supported by a Boehringer-Ingelheim fellowship and AW was partly supported by a fellowship from the Austrian Academy of Sciences.",

year = "2008",

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doi = "10.1016/j.sbi.2007.11.005",

language = "English (US)",

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T1 - The termination of translation

AU - Petry, Sabine

AU - Weixlbaumer, Albert

AU - Ramakrishnan, V.

N1 - Funding Information: Work in the authors’ laboratory was supported by the Medical Research Council (UK) and grants from the US National Institutes of Health and the Agouron Institute. SP was partly supported by a Boehringer-Ingelheim fellowship and AW was partly supported by a fellowship from the Austrian Academy of Sciences.

PY - 2008/2

Y1 - 2008/2

N2 - Recent results from cryoelectron microscopy, crystallography, and biochemical experiments have shed considerable light on the process by which protein synthesis is terminated when a stop codon is reached. However, a detailed understanding of the underlying mechanisms will require higher-resolution structures of the various states involved.

AB - Recent results from cryoelectron microscopy, crystallography, and biochemical experiments have shed considerable light on the process by which protein synthesis is terminated when a stop codon is reached. However, a detailed understanding of the underlying mechanisms will require higher-resolution structures of the various states involved.

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U2 - 10.1016/j.sbi.2007.11.005

DO - 10.1016/j.sbi.2007.11.005

M3 - Review article

C2 - 18206363

AN - SCOPUS:39149107772

SN - 0959-440X

VL - 18

SP - 70

EP - 77

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

IS - 1

ER -

The termination of translation

Abstract

All Science Journal Classification (ASJC) codes

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