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The small intestine shields the liver from fructose-induced steatosis
Cholsoon Jang
, Shogo Wada
, Steven Yang
, Bridget Gosis
, Xianfeng Zeng
, Zhaoyue Zhang
, Yihui Shen
, Gina Lee
, Zoltan Arany
,
Joshua D. Rabinowitz
Chemistry
High Meadows Environmental Institute
Lewis-Sigler Institute for Integrative Genomics
Molecular Biology
Princeton Branch of the Ludwig Institute for Cancer Research
Research output
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Contribution to journal
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Article
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peer-review
128
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Keyphrases
Liver
100%
Fructose
100%
Small Intestine
100%
Steatosis
100%
Ketohexokinase
30%
Lipogenesis
23%
High Fructose
15%
Fructose Metabolism
15%
Intestine-specific
15%
Fructose Consumption
15%
Alternative Splicing
7%
Overexpression
7%
Phosphorylation
7%
Isozymes
7%
Obesity
7%
Gut Microbiota
7%
Food Availability
7%
Metabolic Syndrome
7%
Catabolism
7%
Modern Context
7%
Hepatic Steatosis
7%
Intake Rate
7%
Lipogenic
7%
Over 45
7%
Epidemiological Study
7%
Capacity Control
7%
Fructose Absorption
7%
Gavage
7%
Dietary Intake
7%
Hepatic Lipogenesis
7%
Non-alcoholic Fatty Liver Disease (NAFLD)
7%
Fructose Intake
7%
Liver Pathology
7%
Multiple Dose
7%
Mouse Intestine
7%
Fructose Conversion
7%
Sweet Drinks
7%
Medicine and Dentistry
Small Intestine
100%
Fructose
100%
Steatosis
100%
Ketohexokinase
22%
Lipogenesis
22%
Hyperlipidemia
11%
Fructose Metabolism
11%
Enzymes
5%
Gut Microbiota
5%
Drive
5%
Metabolic Syndrome
5%
Metabolite
5%
Food Availability
5%
Head
5%
Dietary Intake
5%
Feeding
5%
Fatty Liver
5%
Intestinal Clearance
5%
Liver Pathology
5%
Multiple Drug Dose
5%
Nonalcoholic Fatty Liver
5%
phosphorylation
5%
Catabolism
5%
Isoenzyme
5%