The secondary attachment site for bacteriophage λ in the pro A B gene of Escherichia coli

Jennifer L. Pinkham, Terry Platt, Lynn W. Enquist, Robert A. Weisberg

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We have determined the nucleotide sequence of a secondary λ attachment site in pro A B, a site that accounts for 3% of lysogens isolated from Escherichia coli strains deleted for the primary site. Direct sequence analysis of the transducing bacteriophages carrying the left and right att junctions, as well as the recombinant pro+ phage reveals that the pro A B site shares an 11-nucleotide interrupted homology with the core sequence of the primary site. We have compared the pro A Batt site with other secondary attachment sites to gain insights into the structural features important for λ integration.

Original languageEnglish (US)
Pages (from-to)587-592
Number of pages6
JournalJournal of Molecular Biology
Volume144
Issue number4
DOIs
StatePublished - Dec 25 1980
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

Fingerprint Dive into the research topics of 'The secondary attachment site for bacteriophage λ in the pro A B gene of Escherichia coli'. Together they form a unique fingerprint.

Cite this