The promise and limitations of population exomics for human evolution studies

Jacob A. Tennessen; Timothy D. O'Connor; Michael J. Bamshad; Joshua M. Akey

doi:10.1186/gb-2011-12-9-127

The promise and limitations of population exomics for human evolution studies

Jacob A. Tennessen
, Timothy D. O'Connor
, Michael J. Bamshad
, Joshua M. Akey

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Exome sequencing is poised to yield substantial insights into human genetic variation and evolutionary history, but there are significant challenges to overcome before this becomes a reality.

Original language	English (US)
Article number	127
Journal	Genome biology
Volume	12
Issue number	9
DOIs	https://doi.org/10.1186/gb-2011-12-9-127
State	Published - Sep 14 2011
Externally published	Yes

All Science Journal Classification (ASJC) codes

Genetics
Ecology, Evolution, Behavior and Systematics
Cell Biology

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10.1186/gb-2011-12-9-127

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title = "The promise and limitations of population exomics for human evolution studies",

abstract = "Exome sequencing is poised to yield substantial insights into human genetic variation and evolutionary history, but there are significant challenges to overcome before this becomes a reality.",

author = "Tennessen, \{Jacob A.\} and O'Connor, \{Timothy D.\} and Bamshad, \{Michael J.\} and Akey, \{Joshua M.\}",

note = "Funding Information: This work was supported by a research grant (1R01GM076036) from the NIH to JMA and the NHLBI Go Exome sequencing Project (HL-102923) to JMA and MJB.",

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AU - Bamshad, Michael J.

AU - Akey, Joshua M.

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N2 - Exome sequencing is poised to yield substantial insights into human genetic variation and evolutionary history, but there are significant challenges to overcome before this becomes a reality.

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JO - Genome biology

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The promise and limitations of population exomics for human evolution studies

Abstract

All Science Journal Classification (ASJC) codes

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