Abstract
Psychology and microbiology make unlikely friends, but the past decade has witnessed striking bidirectional associations between intrinsic gut microbes and the brain, relationships with largely untested psychological implications. Although microbe–brain relationships are receiving a great deal of attention in biomedicine and neuroscience, psychologists have yet to join this journey. Here, we illustrate microbial associations with emotion, cognition, and social behavior. However, despite considerable enthusiasm and potential, technical and conceptual limitations including low statistical power and lack of mechanistic descriptions prevent a nuanced understanding of microbiome–brain–behavior relationships. Our goal is to describe microbial effects in domains of cognitive significance and the associated challenges to stimulate interdisciplinary research on the contribution of this hidden kingdom to psychological processes.
Original language | English (US) |
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Pages (from-to) | 611-636 |
Number of pages | 26 |
Journal | Trends in Cognitive Sciences |
Volume | 22 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2018 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Neuropsychology and Physiological Psychology
- Experimental and Cognitive Psychology
- Cognitive Neuroscience
Keywords
- antibiotics
- commensal bacteria
- gut–brain axis
- hypothalamic-pituitary-adrenal axis
- interkingdom signaling
- microbiome
- microbiota
- prebiotics
- probiotics
- psychobiotics