The mammalian embryo’s first agenda: Making trophectoderm

Eszter Posfai, Isidora Rovic, Andrea Jurisicova

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


One of the bottlenecks for a successful pregnancy in mammalian species is the implantation of the early embryo into the wall of the mother’s uterus.The first cell lineage the embryo sets aside following fertilization is the trophectoderm – a specialized cell type that establishes contact with the mother and mediates embryo implantation. We summarize the events that lead to the formation of the trophectoderm lineage in the preimplantation embryo and highlight key features of this cell type, which could be useful in the clinical setting for prediction of implantation outcomes.

Original languageEnglish (US)
Pages (from-to)157-170
Number of pages14
JournalInternational Journal of Developmental Biology
Issue number3-5
StatePublished - 2019
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Embryology
  • Developmental Biology


  • Implantation
  • Inner cell mass
  • Preimplantation embryo
  • Trophectoderm


Dive into the research topics of 'The mammalian embryo’s first agenda: Making trophectoderm'. Together they form a unique fingerprint.

Cite this