The lambda and p22 phage repressors

Robert T. Sauer; Hillary C.M. Nelson; Kathleen Hehir; Michael H. Hecht; Frederick S. Gimble; Jaime Deanda; Anthony R. Poteete

doi:10.1080/07391102.1983.10507499

The lambda and p22 phage repressors

Robert T. Sauer
, Hillary C.M. Nelson
, Kathleen Hehir
, Michael H. Hecht
, Frederick S. Gimble
, Jaime Deanda
, Anthony R. Poteete

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The lambda cl repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA. protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes.

Original language	English (US)
Pages (from-to)	1011-1022
Number of pages	12
Journal	Journal of Biomolecular Structure and Dynamics
Volume	1
Issue number	4
DOIs	https://doi.org/10.1080/07391102.1983.10507499
State	Published - Dec 1983
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Structural Biology

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10.1080/07391102.1983.10507499

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@article{117d39df61474efda8bf66f12e2f6e2b,

title = "The lambda and p22 phage repressors",

abstract = "The lambda cl repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA. protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes.",

author = "Sauer, \{Robert T.\} and Nelson, \{Hillary C.M.\} and Kathleen Hehir and Hecht, \{Michael H.\} and Gimble, \{Frederick S.\} and Jaime Deanda and Poteete, \{Anthony R.\}",

note = "Funding Information: We thank Carl Pabo and Mitch Lewis for discussions and information concerning the crystal structure of lambda repressor's N-terminal domain. Some of the work described here was supported by NIH grant AI-16892 to RTS and a grant from the Dept. of Molecular Genetics and Microbiology to ARP.",

year = "1983",

month = dec,

doi = "10.1080/07391102.1983.10507499",

language = "English (US)",

volume = "1",

pages = "1011--1022",

journal = "Journal of Biomolecular Structure and Dynamics",

issn = "0739-1102",

publisher = "Taylor and Francis Ltd.",

number = "4",

}

TY - JOUR

T1 - The lambda and p22 phage repressors

AU - Sauer, Robert T.

AU - Nelson, Hillary C.M.

AU - Hehir, Kathleen

AU - Hecht, Michael H.

AU - Gimble, Frederick S.

AU - Deanda, Jaime

AU - Poteete, Anthony R.

N1 - Funding Information: We thank Carl Pabo and Mitch Lewis for discussions and information concerning the crystal structure of lambda repressor's N-terminal domain. Some of the work described here was supported by NIH grant AI-16892 to RTS and a grant from the Dept. of Molecular Genetics and Microbiology to ARP.

PY - 1983/12

Y1 - 1983/12

N2 - The lambda cl repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA. protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes.

AB - The lambda cl repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA. protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes.

UR - https://www.scopus.com/pages/publications/0020954218

UR - https://www.scopus.com/pages/publications/0020954218#tab=citedBy

U2 - 10.1080/07391102.1983.10507499

DO - 10.1080/07391102.1983.10507499

M3 - Article

C2 - 6242868

AN - SCOPUS:0020954218

SN - 0739-1102

VL - 1

SP - 1011

EP - 1022

JO - Journal of Biomolecular Structure and Dynamics

JF - Journal of Biomolecular Structure and Dynamics

IS - 4

ER -

The lambda and p22 phage repressors

Abstract

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