The lambda and p22 phage repressors

Robert T. Sauer, Hillary C.M. Nelson, Kathleen Hehir, Michael H. Hecht, Frederick S. Gimble, Jaime Deanda, Anthony R. Poteete

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The lambda cl repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA. protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes.

Original languageEnglish (US)
Pages (from-to)1011-1022
Number of pages12
JournalJournal of Biomolecular Structure and Dynamics
Issue number4
StatePublished - Dec 1983
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology


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