The global threat of antimicrobial resistance: Science for intervention

I. Roca, M. Akova, F. Baquero, J. Carlet, M. Cavaleri, S. Coenen, J. Cohen, D. Findlay, I. Gyssens, O. E. Heure, G. Kahlmeter, H. Kruse, R. Laxminarayan, E. Liébana, L. López-Cerero, A. MacGowan, M. Martins, J. Rodríguez-Baño, J. M. Rolain, C. SegoviaB. Sigauque, E. Taconelli, E. Wellington, J. Vila

Research output: Contribution to journalReview articlepeer-review

786 Scopus citations

Abstract

In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant bacteria are currently considered as an emergent global disease and a major public health problem. The B-Debate meeting brought together renowned experts representing the main stakeholders (i.e. policy makers, public health authorities, regulatory agencies, pharmaceutical companies and the scientific community at large) to review the globalthreat of antibiotic resistance and come up with a coordinated set of strategies to fight antimicrobial resistance in a multifaceted approach. We summarize the views of the B-Debate participants regarding the current situation of antimicrobial resistance in animals and the food chain, within the community and the healthcare setting as well as the role of the environment and the development of novel diagnostic and therapeutic strategies, providing expert recommendations to tackle the global threat of antimicrobial resistance.

Original languageEnglish (US)
Pages (from-to)22-29
Number of pages8
JournalNew Microbes and New Infections
Volume6
DOIs
StatePublished - Jul 1 2015

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases

Keywords

  • Antibiotic consumption
  • Antibiotic resistance
  • Antibiotic stewardship
  • Antibiotics as growth promoters
  • Drug discovery
  • Infection control measures
  • Multidrug resistant bacteria
  • Self-medication
  • Surveillance
  • Wastewater treatment plants

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