The genetics of protein secretion in E. coli

Kristina L. Bieker; Thomas J. Silhavy

doi:10.1016/0168-9525(90)90254-4

The genetics of protein secretion in E. coli

Kristina L. Bieker, Thomas J. Silhavy

Molecular Biology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.

Original language	English (US)
Pages (from-to)	329-334
Number of pages	6
Journal	Trends in Genetics
Volume	6
Issue number	C
DOIs	https://doi.org/10.1016/0168-9525(90)90254-4
State	Published - 1990

All Science Journal Classification (ASJC) codes

Genetics

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10.1016/0168-9525(90)90254-4

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title = "The genetics of protein secretion in E. coli",

abstract = "Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.",

author = "Bieker, {Kristina L.} and Silhavy, {Thomas J.}",

note = "Funding Information: We wish to thank members of the lab for helpful comments. In addition, we thank Susan DiRenzo for help with the manuscript. This work was supported by an NIH grant to T.J.S. (GM34821). K.L.B. was supported by Public Health Service Training Grant 5T326M07312.",

year = "1990",

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T1 - The genetics of protein secretion in E. coli

AU - Bieker, Kristina L.

AU - Silhavy, Thomas J.

N1 - Funding Information: We wish to thank members of the lab for helpful comments. In addition, we thank Susan DiRenzo for help with the manuscript. This work was supported by an NIH grant to T.J.S. (GM34821). K.L.B. was supported by Public Health Service Training Grant 5T326M07312.

PY - 1990

Y1 - 1990

N2 - Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.

AB - Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.

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The genetics of protein secretion in E. coli

Abstract

All Science Journal Classification (ASJC) codes

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