The genetics of protein secretion in E. coli

Kristina L. Bieker, Thomas J. Silhavy

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalTrends in Genetics
Issue numberC
StatePublished - 1990

All Science Journal Classification (ASJC) codes

  • Genetics


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