The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO

Medicine & Life Sciences

• Biological Phenomena 6%
• Caenorhabditis elegans 22%
• Co-Repressor Proteins 8%
• Gene Expression Profiling 6%
• Genes 8%
• Host Factor 1 Protein 100%
• Longevity 48%
• Mammals 5%
• Mutation 3%
• Oxidative Stress 4%
• Proteins 9%
• Transcription Factors 5%

Agriculture & Biology

• Caenorhabditis elegans 24%
• cells 2%
• gene expression 4%
• genes 7%
• host-cell factors 96%
• mammals 5%
• mutation 5%
• oxidative stress 6%
• proteins 10%
• stress response 18%
• transcription (genetics) 5%
• transcription factors 5%

Earth & Environmental Sciences

• biological processes 6%
• cell 33%
• gene 15%
• gene expression 7%
• mammal 5%
• mutation 6%
• oxidative stress 7%
• protein 19%
• regulation 9%
• SIR 71%