The effect of global travel on the spread of SARS

Shigui Ruan, Wendi Wang, Simon Asher Levin

Research output: Contribution to journalArticlepeer-review

98 Scopus citations


The goal of this paper is to study the global spread of SARS. We propose a multiregional compartmental model using medical geography theory (central place theory) and regarding each outbreak zone (such as Hong Kong, Singapore, Toronto, and Beijing) as one region. We then study the effect of the travel of individuals (especially the infected and exposed ones) between regions on the global spread of the disease.

Original languageEnglish (US)
Pages (from-to)205-218
Number of pages14
JournalMathematical Biosciences and Engineering
Issue number1
StatePublished - Jan 2006

All Science Journal Classification (ASJC) codes

  • Modeling and Simulation
  • General Agricultural and Biological Sciences
  • Computational Mathematics
  • Applied Mathematics


  • Basic reproduction number
  • Central place theory
  • Epidemic model
  • Global travel
  • Medical geography


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