Abstract
The essential histone chaperone FACT controls chromatin integrity in cooperation with H2B ubiquitination. Murawska et al. reveal how H2Bub regulates FACT activity within gene bodies and identify a novel role for the FACT complex at highly compacted chromosomal regions.
Original language | English (US) |
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Pages (from-to) | 501-513.e7 |
Journal | Molecular Cell |
Volume | 77 |
Issue number | 3 |
DOIs | |
State | Published - Feb 6 2020 |
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology
Keywords
- FACT
- H2B ubiquitination
- S. pombe
- chromatin structure
- histone chaperone