@article{f367aeb86e9d4de6a624e985c19ce84e,
title = "The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions",
abstract = "The essential histone chaperone FACT controls chromatin integrity in cooperation with H2B ubiquitination. Murawska et al. reveal how H2Bub regulates FACT activity within gene bodies and identify a novel role for the FACT complex at highly compacted chromosomal regions.",
keywords = "FACT, H2B ubiquitination, S. pombe, chromatin structure, histone chaperone",
author = "Magdalena Murawska and Tamas Schauer and Atsushi Matsuda and Wilson, {Marcus D.} and Thomas Pysik and Felix Wojcik and Muir, {Tom W.} and Yasushi Hiraoka and Tobias Straub and Ladurner, {Andreas G.}",
note = "Funding Information: We thank Alexander Brehm and Fred Winston for insightful comments on the manuscript and Carla Margulies for advice. We thank Sigurd Braun, Philipp Korber and Silke Krause for sharing protocols and Julia Prei{\ss}er for help with cell culture. We thank LAFUGA and Stefan Krebs and Helmut Blum for sequencing. This research was supported by the European Commission (Marie-Curie Individual Fellowship H2020-MSCA-IF-2014 contract 657244 to M.M.), the Friedrich-Baur-Stiftung (to M.M.), DFG SFB1064 and DFG SFB1309 Collaborative Research Centers (to A.G.L.), Z04/SFB1064 to T. Straub and T. Schauer, NIH ( R37 GM086868 , R01 GM107047 , and P01 CA196539 to T.W.M.), and JSPS KAKENHI ( JP19H03202 to A.M.). F.W. was funded by a postdoctoral fellowship from DFG ( WO 2039/1-1 ). M.D.W. is supported by the Wellcome Trust ( 210493 ) and University of Edinburgh . The Wellcome Centre for Cell Biology is supported by core funding from the Wellcome Trust ( 203149 ). Publisher Copyright: {\textcopyright} 2019",
year = "2020",
month = feb,
day = "6",
doi = "10.1016/j.molcel.2019.11.016",
language = "English (US)",
volume = "77",
pages = "501--513.e7",
journal = "Molecular Cell",
issn = "1097-2765",
publisher = "Cell Press",
number = "3",
}