The Cerebellum, Sensitive Periods, and Autism

Samuel S.H. Wang, Alexander D. Kloth, Aleksandra Badura

Research output: Contribution to journalReview article

273 Scopus citations

Abstract

Cerebellar research has focused principally on adult motor function. However, the cerebellum also maintains abundant connections with nonmotor brain regions throughout postnatal life. Here we review evidence that the cerebellum may guide the maturation of remote nonmotor neural circuitry and influence cognitive development, with a focus on its relationship with autism. Specific cerebellar zones influence neocortical substrates for social interaction, and we propose that sensitive-period disruption of such internal brain communication can account for autism's key features.

Original languageEnglish (US)
Pages (from-to)518-532
Number of pages15
JournalNeuron
Volume83
Issue number3
DOIs
StatePublished - Aug 6 2014

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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