The Capsella rubella genome and the genomic consequences of rapid mating system evolution

Tanja Slotte, Khaled M. Hazzouri, J. Arvid Ågren, Daniel Koenig, Florian Maumus, Ya Long Guo, Kim Steige, Adrian E. Platts, Juan S. Escobar, L. Killian Newman, Wei Wang, Terezie Mandáková, Emilio Vello, Lisa M. Smith, Stefan R. Henz, Joshua Steffen, Shohei Takuno, Yaniv Brandvain, Graham Coop, Peter AndolfattoTina T. Hu, Mathieu Blanchette, Richard M. Clark, Hadi Quesneville, Magnus Nordborg, Brandon S. Gaut, Martin A. Lysak, Jerry Jenkins, Jane Grimwood, Jarrod Chapman, Simon Prochnik, Shengqiang Shu, Daniel Rokhsar, Jeremy Schmutz, Detlef Weigel, Stephen I. Wright

Research output: Contribution to journalArticle

206 Scopus citations

Abstract

The shift from outcrossing to selfing is common in flowering plants, but the genomic consequences and the speed at which they emerge remain poorly understood. An excellent model for understanding the evolution of self fertilization is provided by Capsella rubella, which became self compatible <200,000 years ago. We report a C. rubella reference genome sequence and compare RNA expression and polymorphism patterns between C. rubella and its outcrossing progenitor Capsella grandiflora. We found a clear shift in the expression of genes associated with flowering phenotypes, similar to that seen in Arabidopsis, in which self fertilization evolved about 1 million years ago. Comparisons of the two Capsella species showed evidence of rapid genome-wide relaxation of purifying selection in C. rubella without a concomitant change in transposable element abundance. Overall we document that the transition to selfing may be typified by parallel shifts in gene expression, along with a measurable reduction of purifying selection.

Original languageEnglish (US)
Pages (from-to)831-835
Number of pages5
JournalNature Genetics
Volume45
Issue number7
DOIs
StatePublished - Jul 1 2013

All Science Journal Classification (ASJC) codes

  • Genetics

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    Slotte, T., Hazzouri, K. M., Ågren, J. A., Koenig, D., Maumus, F., Guo, Y. L., Steige, K., Platts, A. E., Escobar, J. S., Newman, L. K., Wang, W., Mandáková, T., Vello, E., Smith, L. M., Henz, S. R., Steffen, J., Takuno, S., Brandvain, Y., Coop, G., ... Wright, S. I. (2013). The Capsella rubella genome and the genomic consequences of rapid mating system evolution. Nature Genetics, 45(7), 831-835. https://doi.org/10.1038/ng.2669