The Biochemical Evolution of Protein Complexes

Todd M. Greco; Ileana M. Cristea

doi:10.1016/j.tibs.2015.11.007

The Biochemical Evolution of Protein Complexes

Todd M. Greco, Ileana M. Cristea

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.

Original language	English (US)
Pages (from-to)	4-6
Number of pages	3
Journal	Trends in Biochemical Sciences
Volume	41
Issue number	1
DOIs	https://doi.org/10.1016/j.tibs.2015.11.007
State	Published - Jan 1 2016

All Science Journal Classification (ASJC) codes

Molecular Biology
Biochemistry

Keywords

Evolution
Interactome
Macromolecular complex
Mass spectrometry
Protein interactions
Protein-protein interaction

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10.1016/j.tibs.2015.11.007

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title = "The Biochemical Evolution of Protein Complexes",

abstract = "Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.",

keywords = "Evolution, Interactome, Macromolecular complex, Mass spectrometry, Protein interactions, Protein-protein interaction",

author = "Greco, {Todd M.} and Cristea, {Ileana M.}",

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year = "2016",

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T1 - The Biochemical Evolution of Protein Complexes

AU - Greco, Todd M.

AU - Cristea, Ileana M.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.

AB - Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.

KW - Evolution

KW - Interactome

KW - Macromolecular complex

KW - Mass spectrometry

KW - Protein interactions

KW - Protein-protein interaction

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DO - 10.1016/j.tibs.2015.11.007

M3 - Short survey

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AN - SCOPUS:84951848923

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SP - 4

EP - 6

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

IS - 1

ER -

The Biochemical Evolution of Protein Complexes

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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