Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture

Victor Stollar; Joseph Peleg; Thomas E. Shenk

doi:10.1159/000149441

Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture

Victor Stollar, Joseph Peleg, Thomas E. Shenk

Molecular Biology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

SV-S, a cloned small plaque mutant of Sindbis virus derived from persistently infected A odes aegypti cell cultures, was shown also to be an RNA temperature-sensitive mutant. It interfered with the replication of SV-W at the nonpermissive temperature as well as the permissive temperature, but did not depress net viral RNA synthesis in cells coinfected with SV-W.

Original language	English (US)
Pages (from-to)	337-344
Number of pages	8
Journal	Intervirology
Volume	2
Issue number	5-6
DOIs	https://doi.org/10.1159/000149441
State	Published - 1973

All Science Journal Classification (ASJC) codes

Virology
Infectious Diseases

Keywords

Aedes aegypti cells
Persistent infection
Sindbis virus mutant

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10.1159/000149441

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title = "Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture",

abstract = "SV-S, a cloned small plaque mutant of Sindbis virus derived from persistently infected A odes aegypti cell cultures, was shown also to be an RNA temperature-sensitive mutant. It interfered with the replication of SV-W at the nonpermissive temperature as well as the permissive temperature, but did not depress net viral RNA synthesis in cells coinfected with SV-W.",

keywords = "Aedes aegypti cells, Persistent infection, Sindbis virus mutant",

author = "Victor Stollar and Joseph Peleg and Shenk, {Thomas E.}",

year = "1973",

doi = "10.1159/000149441",

language = "English (US)",

volume = "2",

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journal = "Intervirology",

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TY - JOUR

T1 - Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture

AU - Stollar, Victor

AU - Peleg, Joseph

AU - Shenk, Thomas E.

PY - 1973

Y1 - 1973

N2 - SV-S, a cloned small plaque mutant of Sindbis virus derived from persistently infected A odes aegypti cell cultures, was shown also to be an RNA temperature-sensitive mutant. It interfered with the replication of SV-W at the nonpermissive temperature as well as the permissive temperature, but did not depress net viral RNA synthesis in cells coinfected with SV-W.

AB - SV-S, a cloned small plaque mutant of Sindbis virus derived from persistently infected A odes aegypti cell cultures, was shown also to be an RNA temperature-sensitive mutant. It interfered with the replication of SV-W at the nonpermissive temperature as well as the permissive temperature, but did not depress net viral RNA synthesis in cells coinfected with SV-W.

KW - Aedes aegypti cells

KW - Persistent infection

KW - Sindbis virus mutant

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U2 - 10.1159/000149441

DO - 10.1159/000149441

M3 - Article

AN - SCOPUS:0016224491

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JO - Intervirology

JF - Intervirology

IS - 5-6

ER -

Temperature sensitivity of a sindbis virus mutant isolated from persistently infected Aedes aegypti cell culture

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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