Telomeric position effect in yeast

Lisa L. Sandell, Virginia A. Zakian

Research output: Contribution to journalReview article

50 Scopus citations

Abstract

Telomeres are the physical ends of chromosomes. In yeast, when a gene is placed near a telomere, its transcription is repressed. Genes under the influence of this telomeric position effects switch between a repressed state and a transcriptionally active state, each of which is stable for many cell generations. Telomeric position effect may provide a model system for the study of heritable gene regulation in other, more complex organisms.

Original languageEnglish (US)
Pages (from-to)10-14
Number of pages5
JournalTrends in Cell Biology
Volume2
Issue number1
DOIs
StatePublished - Jan 1992

All Science Journal Classification (ASJC) codes

  • Cell Biology

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