Telomeres: The beginnings and ends of eukaryotic chromosomes

Virginia A. Zakian

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations


The ends of eukaryotic chromosomes are called telomeres. This article provides a short history of telomere and telomerase research starting with the pioneering work of Muller and McClintock through the molecular era of telomere biology. These studies culminated in the 2009 Nobel Prize in Medicine. Critical findings that moved the field forward and that suggest directions for future research are emphasized.

Original languageEnglish (US)
Pages (from-to)1456-1460
Number of pages5
JournalExperimental Cell Research
Issue number12
StatePublished - Jul 15 2012

All Science Journal Classification (ASJC) codes

  • Cell Biology


  • Chromosome
  • Replication
  • Telomerase
  • Telomere


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