Telomeres: The beginnings and ends of eukaryotic chromosomes

Virginia A. Zakian

doi:10.1016/j.yexcr.2012.02.015

Telomeres: The beginnings and ends of eukaryotic chromosomes

Virginia A. Zakian

Molecular Biology

Research output: Contribution to journal › Review article › peer-review

74 Scopus citations

Abstract

The ends of eukaryotic chromosomes are called telomeres. This article provides a short history of telomere and telomerase research starting with the pioneering work of Muller and McClintock through the molecular era of telomere biology. These studies culminated in the 2009 Nobel Prize in Medicine. Critical findings that moved the field forward and that suggest directions for future research are emphasized.

Original language	English (US)
Pages (from-to)	1456-1460
Number of pages	5
Journal	Experimental Cell Research
Volume	318
Issue number	12
DOIs	https://doi.org/10.1016/j.yexcr.2012.02.015
State	Published - Jul 15 2012

All Science Journal Classification (ASJC) codes

Cell Biology

Keywords

Chromosome
Replication
Telomerase
Telomere

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10.1016/j.yexcr.2012.02.015

Cite this

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title = "Telomeres: The beginnings and ends of eukaryotic chromosomes",

abstract = "The ends of eukaryotic chromosomes are called telomeres. This article provides a short history of telomere and telomerase research starting with the pioneering work of Muller and McClintock through the molecular era of telomere biology. These studies culminated in the 2009 Nobel Prize in Medicine. Critical findings that moved the field forward and that suggest directions for future research are emphasized.",

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AB - The ends of eukaryotic chromosomes are called telomeres. This article provides a short history of telomere and telomerase research starting with the pioneering work of Muller and McClintock through the molecular era of telomere biology. These studies culminated in the 2009 Nobel Prize in Medicine. Critical findings that moved the field forward and that suggest directions for future research are emphasized.

KW - Chromosome

KW - Replication

KW - Telomerase

KW - Telomere

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DO - 10.1016/j.yexcr.2012.02.015

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JO - Experimental Cell Research

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ER -

Telomeres: The beginnings and ends of eukaryotic chromosomes

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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