Task-Dependent Changes in the Large-Scale Dynamics and Necessity of Cortical Regions

Lucas Pinto, Kanaka Rajan, Brian DePasquale, Stephan Y. Thiberge, David W. Tank, Carlos D. Brody

Research output: Contribution to journalArticlepeer-review

119 Scopus citations


Pinto et al. show that more complex perceptual decisions engage more diverse and spatially distributed computations across the cortex than simpler decisions, even when sensory stimuli and motor output are held constant.

Original languageEnglish (US)
Pages (from-to)810-824.e9
Issue number4
StatePublished - Nov 20 2019

All Science Journal Classification (ASJC) codes

  • General Neuroscience


  • RNN
  • cortex
  • decision making
  • evidence accumulation
  • mouse behavior
  • optogenetics
  • virtual reality
  • widefield Ca imaging
  • working memory

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