@inbook{6b717e0b5907471ebc917f4047b7121b,
title = "Taking risks in complex synthesis design",
abstract = "This chapter defines risk-taking in organic synthesis as the deliberate pursuit of strategies that do not have near neighbors in the chemical literature. In these ventures into the unknown, chemical behavior can be difficult to predict. The literature of organic chemistry is replete with examples of powerful, bond-forming strategies that had little or no precedent when they were developed. This essay addresses some of those examples in an effort to demonstrate the merits of creative risk-taking in the planning and execution of organic syntheses.",
author = "Sorensen, {Erik J.} and Siler, {David A.} and Mighion, {Jeffrey D.}",
note = "Funding Information: For our work in the area of organic synthesis, we are extraordinarily grateful to financial support from the National Institute of General Medical Sciences (GM065483) and Princeton University.",
year = "2013",
doi = "10.1016/B978-0-08-099362-1.00009-6",
language = "English (US)",
isbn = "9780080993621",
series = "Strategies and Tactics in Organic Synthesis",
publisher = "Academic Press Inc.",
pages = "249--273",
booktitle = "Strategies and Tactics in Organic Synthesis",
address = "United States",
}