Tailoring polymeric hydrogels through cyclodextrin host-guest complexation

Xuhong Guo; Jie Wang; Li Li; Duc Truc Pham; Philip Clements; Stephen F. Lincoln; Bruce L. May; Oingchuan Chen; Li Zheng; Robert K. Prud'Homme

doi:10.1002/marc.200900560

Tailoring polymeric hydrogels through cyclodextrin host-guest complexation

Xuhong Guo, Jie Wang, Li Li, Duc Truc Pham, Philip Clements, Stephen F. Lincoln, Bruce L. May, Oingchuan Chen, Li Zheng, Robert K. Prud'Homme

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A close correlation between molecular-level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β-cyclodextrin (β-CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host-guest complexation between β-CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra- and intermolecular host-guest complexation are found to control poly(acrylate) isomeric inter-strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials. (Figure Presented)

Original language	English (US)
Pages (from-to)	300-304
Number of pages	5
Journal	Macromolecular Rapid Communications
Volume	31
Issue number	3
DOIs	https://doi.org/10.1002/marc.200900560
State	Published - Feb 2 2010

All Science Journal Classification (ASJC) codes

Materials Chemistry
Polymers and Plastics
Organic Chemistry

Keywords

Cyclodextrin
Host-guest complexation
Hydrogels
Polyelectrolytes

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10.1002/marc.200900560

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title = "Tailoring polymeric hydrogels through cyclodextrin host-guest complexation",

abstract = "A close correlation between molecular-level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β-cyclodextrin (β-CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host-guest complexation between β-CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra- and intermolecular host-guest complexation are found to control poly(acrylate) isomeric inter-strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials. (Figure Presented)",

keywords = "Cyclodextrin, Host-guest complexation, Hydrogels, Polyelectrolytes",

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T1 - Tailoring polymeric hydrogels through cyclodextrin host-guest complexation

AU - Guo, Xuhong

AU - Wang, Jie

AU - Li, Li

AU - Pham, Duc Truc

AU - Clements, Philip

AU - Lincoln, Stephen F.

AU - May, Bruce L.

AU - Chen, Oingchuan

AU - Zheng, Li

AU - Prud'Homme, Robert K.

PY - 2010/2/2

Y1 - 2010/2/2

N2 - A close correlation between molecular-level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β-cyclodextrin (β-CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host-guest complexation between β-CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra- and intermolecular host-guest complexation are found to control poly(acrylate) isomeric inter-strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials. (Figure Presented)

AB - A close correlation between molecular-level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β-cyclodextrin (β-CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host-guest complexation between β-CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra- and intermolecular host-guest complexation are found to control poly(acrylate) isomeric inter-strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials. (Figure Presented)

KW - Cyclodextrin

KW - Host-guest complexation

KW - Hydrogels

KW - Polyelectrolytes

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Tailoring polymeric hydrogels through cyclodextrin host-guest complexation

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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