Synthesis of Naphthoquinone Antibiotics: Conjugate Addition/Electrophile Trapping with Acylnickel Carbonylate Anions

M. F. Semmelhack, Leonard Keller, Tadahisa Sato, E. Spiess

Research output: Contribution to journalLetter

30 Scopus citations

Abstract

Conjugate addition of nickel acylate complexes followed by quenching with allyl iodide provide key intermediates for the synthesis of nanaomycin A and frenolicin.

Original languageEnglish (US)
Pages (from-to)4382-4384
Number of pages3
JournalJournal of Organic Chemistry
Volume47
Issue number22
DOIs
StatePublished - Jan 1 1982

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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