Synthesis of ABC taxoid ring systems via a convergent strategy

K. C. Nicolaou; Zhen Yang; Erik J. Sorensen; Masahisa Nakada

doi:10.1039/C39930001024

Synthesis of ABC taxoid ring systems via a convergent strategy

K. C. Nicolaou, Zhen Yang, Erik J. Sorensen, Masahisa Nakada

Chemistry

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42 Scopus citations

Abstract

Intermediates 4 and 5have been coupled via a Shapiro reaction to afford compound 6 which has been further elaborated to the ABCtaxcid systems 11and 12 via a McMurry pinacol cyclization to 11followed by oxidation to 12.

Original language	English (US)
Pages (from-to)	1024-1026
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	12
DOIs	https://doi.org/10.1039/C39930001024
State	Published - 1993

All Science Journal Classification (ASJC) codes

Molecular Medicine

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title = "Synthesis of ABC taxoid ring systems via a convergent strategy",

abstract = "Intermediates 4 and 5have been coupled via a Shapiro reaction to afford compound 6 which has been further elaborated to the ABCtaxcid systems 11and 12 via a McMurry pinacol cyclization to 11followed by oxidation to 12.",

author = "Nicolaou, {K. C.} and Zhen Yang and Sorensen, {Erik J.} and Masahisa Nakada",

year = "1993",

doi = "10.1039/C39930001024",

language = "English (US)",

pages = "1024--1026",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Royal Society of Chemistry",

number = "12",

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T1 - Synthesis of ABC taxoid ring systems via a convergent strategy

AU - Nicolaou, K. C.

AU - Yang, Zhen

AU - Sorensen, Erik J.

AU - Nakada, Masahisa

PY - 1993

Y1 - 1993

N2 - Intermediates 4 and 5have been coupled via a Shapiro reaction to afford compound 6 which has been further elaborated to the ABCtaxcid systems 11and 12 via a McMurry pinacol cyclization to 11followed by oxidation to 12.

AB - Intermediates 4 and 5have been coupled via a Shapiro reaction to afford compound 6 which has been further elaborated to the ABCtaxcid systems 11and 12 via a McMurry pinacol cyclization to 11followed by oxidation to 12.

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U2 - 10.1039/C39930001024

DO - 10.1039/C39930001024

M3 - Article

AN - SCOPUS:37049088176

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EP - 1026

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 12

ER -

Synthesis of ABC taxoid ring systems via a convergent strategy

Abstract

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