Synthesis of (5.R,10S,11R)-( + )-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imin-11-ol: A Hydroxylated Metabolite of MK-0801

Chemistry

• Oxazolidinone 100%
• Metabolite 100%
• Methanol 50%
• Aziridine 50%
• Ring Opening Reaction 50%
• Enantiomer 50%
• Stereochemistry 50%
• Acetyl 50%

Keyphrases

• Hydroxylated Metabolites 100%
• Selective Ring Opening 50%
• Bromohydrin 50%
• Carbinols 50%
• Acid-catalyzed Cyclization 50%
• Acetyl Bromide 50%
• Dibenzosuberenone 50%