Abstract
This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the postgenome era, but in many ways are leading the way to the promise of a "systems-level" understanding of complex processes such as notochord formation, neurogenesis, and even behavior.
Original language | English (US) |
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Pages (from-to) | 2407-2411 |
Number of pages | 5 |
Journal | Genes and Development |
Volume | 19 |
Issue number | 20 |
DOIs | |
State | Published - Oct 15 2005 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Genetics
- Developmental Biology
Keywords
- Ascidians
- Ciona
- Gene networks
- Genomics
- Morphogenesis