Surfing with the tunicates into the post-genome era

Nori Satoh, Mike Levine

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

This year is the centenary of Edward G. Conklin's signal findings in embryology: the elucidation of complete cell lineages and the discovery of localized maternal determinants. Conklin used ascidian embryos to elucidate universal principles in embryology. A century later, ascidians, or sea squirts, have not only entered the postgenome era, but in many ways are leading the way to the promise of a "systems-level" understanding of complex processes such as notochord formation, neurogenesis, and even behavior.

Original languageEnglish (US)
Pages (from-to)2407-2411
Number of pages5
JournalGenes and Development
Volume19
Issue number20
DOIs
StatePublished - Oct 15 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology

Keywords

  • Ascidians
  • Ciona
  • Gene networks
  • Genomics
  • Morphogenesis

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