Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42

Keyphrases

• Alzheimer 100%
• Structure-activity Relationship 100%
• Transgenic Fly 100%
• High-throughput Screening 66%
• Locomotive 66%
• Central Nervous System 33%
• Alzheimer's Disease 33%
• Cytotoxicity 33%
• Aromatic Ring 33%
• Rational Design 33%
• Parent Compounds 33%
• Small Molecule Inhibitors 33%
• Amyloid beta 33%
• Effective Strategies 33%
• Alzheimer's Disease Model 33%
• Fluorine Substitution 33%
• Chemical Features 33%
• Drosophila Melanogaster Model 33%
• Alzheime's Disease 33%
• High-resolution Structure 33%
• D830 33%

Chemistry

• Structure-Activity Relationship 100%
• High Throughput Screening 100%
• Peptide 100%
• Toxic 50%
• Aromatic Structure 50%
• Fluorine 50%
• Beta-Amyloid 50%
• formation 50%
• Oligomer 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Alzheimer's Disease 100%
• Structure Activity Relationship 100%
• Peptide 100%
• High-Throughput Screening 66%
• Drosophila Melanogaster 33%
• Amyloid Protein 33%
• Cytotoxicity 33%
• Oligomer 33%