Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1

Keyphrases

• RNA Surveillance 100%
• Double-stranded RNA 100%
• Oligoadenylate Synthetase 100%
• RNA-protein Interaction 20%
• 2-5A 20%
• CRISTAL 20%
• Cell Differentiation 10%
• Carbonyl 10%
• Active Site Structure 10%
• Sequence Specificity 10%
• Polymerized 10%
• RNA Binding 10%
• RNA Recognition 10%
• Mg2+ 10%
• Uncharacterized Proteins 10%
• Conformational Change 10%
• Coordination Geometry 10%
• Innate Immunity Cells 10%
• Minor Groove 10%
• RNA Activation (RNAa) 10%
• Conformational Rearrangement 10%
• OAS1 10%
• Human Sensors 10%
• Terminal Lobes 10%
• Hydrogen Bond (H-bond) 10%

Biochemistry, Genetics and Molecular Biology

• Double-Stranded RNA 100%
• RNA 30%
• Adenosine Triphosphate 30%
• Crystal Structure 20%
• Cellular Differentiation 10%
• Cell Cycle 10%
• Conformational Change 10%
• Active Site 10%
• Hydrogen Bond 10%
• N-Terminus 10%
• RNA Binding 10%
• Innate Immunity 10%
• OAS1 10%