Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

  • Aaron Balog
  • , Peter Bertinato
  • , Dai Shi Su
  • , Dongfang Meng
  • , Erik Sorensen
  • , Samuel J. Danishefsky
  • , Yu Huang Zheng
  • , Ting Chao Chou
  • , Lifeng He
  • , Susan B. Horwitz

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

Original languageEnglish (US)
Pages (from-to)4529-4532
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number26
DOIs
StatePublished - Jun 30 1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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