Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Aaron Balog; Peter Bertinato; Dai Shi Su; Dongfang Meng; Erik Sorensen; Samuel J. Danishefsky; Yu Huang Zheng; Ting Chao Chou; Lifeng He; Susan B. Horwitz

doi:10.1016/S0040-4039(97)00931-3

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Aaron Balog
, Peter Bertinato
, Dai Shi Su
, Dongfang Meng
, Erik Sorensen
, Samuel J. Danishefsky
, Yu Huang Zheng
, Ting Chao Chou
, Lifeng He
, Susan B. Horwitz

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

Original language	English (US)
Pages (from-to)	4529-4532
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	26
DOIs	https://doi.org/10.1016/S0040-4039(97)00931-3
State	Published - Jun 30 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)00931-3

Cite this

Balog, A., Bertinato, P., Su, D. S., Meng, D., Sorensen, E., Danishefsky, S. J., Zheng, Y. H., Chou, T. C., He, L., & Horwitz, S. B. (1997). Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties. Tetrahedron Letters, 38(26), 4529-4532. https://doi.org/10.1016/S0040-4039(97)00931-3

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title = "Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties",

abstract = "The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.",

author = "Aaron Balog and Peter Bertinato and Su, \{Dai Shi\} and Dongfang Meng and Erik Sorensen and Danishefsky, \{Samuel J.\} and Zheng, \{Yu Huang\} and Chou, \{Ting Chao\} and Lifeng He and Horwitz, \{Susan B.\}",

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doi = "10.1016/S0040-4039(97)00931-3",

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Balog, A, Bertinato, P, Su, DS, Meng, D, Sorensen, E, Danishefsky, SJ, Zheng, YH, Chou, TC, He, L & Horwitz, SB 1997, 'Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties', Tetrahedron Letters, vol. 38, no. 26, pp. 4529-4532. https://doi.org/10.1016/S0040-4039(97)00931-3

TY - JOUR

T1 - Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series

T2 - Some surprising observations regarding their chemical and biological properties

AU - Balog, Aaron

AU - Bertinato, Peter

AU - Su, Dai Shi

AU - Meng, Dongfang

AU - Sorensen, Erik

AU - Danishefsky, Samuel J.

AU - Zheng, Yu Huang

AU - Chou, Ting Chao

AU - He, Lifeng

AU - Horwitz, Susan B.

PY - 1997/6/30

Y1 - 1997/6/30

N2 - The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

AB - The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

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UR - https://www.scopus.com/pages/publications/0030950914#tab=citedBy

U2 - 10.1016/S0040-4039(97)00931-3

DO - 10.1016/S0040-4039(97)00931-3

M3 - Article

AN - SCOPUS:0030950914

SN - 0040-4039

VL - 38

SP - 4529

EP - 4532

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Abstract

All Science Journal Classification (ASJC) codes

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