Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Aaron Balog; Peter Bertinato; Dai Shi Su; Dongfang Meng; Erik Sorensen; Samuel J. Danishefsky; Yu Huang Zheng; Ting Chao Chou; Lifeng He; Susan B. Horwitz

doi:10.1016/S0040-4039(97)00931-3

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Aaron Balog, Peter Bertinato, Dai Shi Su, Dongfang Meng, Erik Sorensen, Samuel J. Danishefsky, Yu Huang Zheng, Ting Chao Chou, Lifeng He, Susan B. Horwitz

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

Original language	English (US)
Pages (from-to)	4529-4532
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	26
DOIs	https://doi.org/10.1016/S0040-4039(97)00931-3
State	Published - Jun 30 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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Balog, A., Bertinato, P., Su, D. S., Meng, D., Sorensen, E., Danishefsky, S. J., Zheng, Y. H., Chou, T. C., He, L., & Horwitz, S. B. (1997). Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties. Tetrahedron Letters, 38(26), 4529-4532. https://doi.org/10.1016/S0040-4039(97)00931-3

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abstract = "The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.",

author = "Aaron Balog and Peter Bertinato and Su, {Dai Shi} and Dongfang Meng and Erik Sorensen and Danishefsky, {Samuel J.} and Zheng, {Yu Huang} and Chou, {Ting Chao} and Lifeng He and Horwitz, {Susan B.}",

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Balog, A, Bertinato, P, Su, DS, Meng, D, Sorensen, E, Danishefsky, SJ, Zheng, YH, Chou, TC, He, L & Horwitz, SB 1997, 'Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties', Tetrahedron Letters, vol. 38, no. 26, pp. 4529-4532. https://doi.org/10.1016/S0040-4039(97)00931-3

TY - JOUR

T1 - Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series

T2 - Some surprising observations regarding their chemical and biological properties

AU - Balog, Aaron

AU - Bertinato, Peter

AU - Su, Dai Shi

AU - Meng, Dongfang

AU - Sorensen, Erik

AU - Danishefsky, Samuel J.

AU - Zheng, Yu Huang

AU - Chou, Ting Chao

AU - He, Lifeng

AU - Horwitz, Susan B.

PY - 1997/6/30

Y1 - 1997/6/30

N2 - The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

AB - The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.

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DO - 10.1016/S0040-4039(97)00931-3

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SN - 0040-4039

VL - 38

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

Abstract

All Science Journal Classification (ASJC) codes

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