Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime

I. W. Davies; M. Taylor; J. F. Marcoux; L. Matty; J. Wu; D. Hughes; P. J. Reider

doi:10.1016/S0040-4039(00)01404-0

Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime

I. W. Davies
, M. Taylor
, J. F. Marcoux
, L. Matty
, J. Wu
, D. Hughes
, P. J. Reider

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94% yield. This reaction is pivotal in the synthesis of cis-aminochromanol. (C) 2000 Elsevier Science Ltd.

Original language	English (US)
Pages (from-to)	8021-8025
Number of pages	5
Journal	Tetrahedron Letters
Volume	41
Issue number	42
DOIs	https://doi.org/10.1016/S0040-4039(00)01404-0
State	Published - Oct 14 2000
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)01404-0

Cite this

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title = "Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime",

abstract = "Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94\% yield. This reaction is pivotal in the synthesis of cis-aminochromanol. (C) 2000 Elsevier Science Ltd.",

author = "Davies, \{I. W.\} and M. Taylor and Marcoux, \{J. F.\} and L. Matty and J. Wu and D. Hughes and Reider, \{P. J.\}",

year = "2000",

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doi = "10.1016/S0040-4039(00)01404-0",

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T1 - Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime

AU - Davies, I. W.

AU - Taylor, M.

AU - Marcoux, J. F.

AU - Matty, L.

AU - Wu, J.

AU - Hughes, D.

AU - Reider, P. J.

PY - 2000/10/14

Y1 - 2000/10/14

N2 - Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94% yield. This reaction is pivotal in the synthesis of cis-aminochromanol. (C) 2000 Elsevier Science Ltd.

AB - Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94% yield. This reaction is pivotal in the synthesis of cis-aminochromanol. (C) 2000 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0034649102

UR - https://www.scopus.com/pages/publications/0034649102#tab=citedBy

U2 - 10.1016/S0040-4039(00)01404-0

DO - 10.1016/S0040-4039(00)01404-0

M3 - Article

AN - SCOPUS:0034649102

SN - 0040-4039

VL - 41

SP - 8021

EP - 8025

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 42

ER -

Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime

Abstract

All Science Journal Classification (ASJC) codes

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